World’s First 3D Bioprinted Live Ear Implant | The Entrepreneurial story of 3D Bio Therapeutics KellyOnTech

World’s First 3D Bioprinted Live Ear Implant | The Entrepreneurial story of 3D Bio Therapeutics KellyOnTech Tech Eco Series
World’s First 3D Bioprinted Live Ear Implant | The Entrepreneurial story of 3D Bio Therapeutics KellyOnTech Tech Eco Series
Alexa, the patient, before the surgery, left, and 30 days after the surgery. Image Credit: Dr. Arturo Bonilla, Microtia-Congenital Ear Institute
Alexa, the patient, before the surgery, left, and 30 days after the surgery. Image Credit: Dr. Arturo Bonilla, Microtia-Congenital Ear Institute

Which company brings new hope to patients?

The company is called 3D Bio Therapeutics, a regenerative medicine clinical-stage biotechnology company founded in 2014. It develops 3D bioprinting and material technologies for the treatment of disease and congenital diseases to deliver safe, functional and personalized living tissues and organs, tailored to patients. The company is also the first to implant 3D bioprinted living tissue into patients.

Image source: 3D Bio Therapeutics, World’s first 3D bioprinted live ear
Image source: 3D Bio Therapeutics, World’s first 3D bioprinted live ear

Why can this company solve the medical challenge of 3D printed living transplants?

The company’s technology focuses on regenerative medicine, solving medical challenges through custom-designed 3D printed living implants. 3D Bio Therapeutics develops living tissue implants with structural and functional integrity through its patented four-part technology platform, include:

  1. 3D bioprinters
  2. bioinks
  3. specialized cell culture systems — to grow living tissue implants with structural and functional integrity.
  4. implantable protective shells — to protect living implants and, thus providing the best treatment results for the patient.

Who founded 3D Bio Therapeutics?

Daniel Cohen, CEO and Co-Founder of 3DBio Therapeutics

Daniel Cohen received his B.S., M.S. and Ph.D. in Mechanical Engineering with minors in Biomedical and Electrical Engineering from Cornell University. He received a National Science Foundation Graduate Research Fellowship and a Department of Homeland Security Graduate Fellowship. Prior to founding 3DBio, he spent four years at McKinsey learning how to commercialize technology projects.

Image source: Business Wire, Daniel Cohen, Co-Founder and CEO of 3D Bio Therapeutics
Image source: Business Wire, Daniel Cohen, Co-Founder and CEO of 3D Bio Therapeutics

Dr. Lawrence Bonassar, Co-Founder of 3D Bio Therapeutics

Dr. Lawrence Bonassar joined Cornell University in 2003 after five years teaching at the Center for Tissue Engineering at the University of Massachusetts Medical School. He completed postdoctoral research at the Massachusetts General Hospital Orthopaedic Research Laboratory and the MIT Centre for Biomedical Engineering.

Image source: Cornell University, Dr. Dr. Lawrence Bonassar, Co-Founder of 3D Bio Therapeutics
Image source: Cornell University, Dr. Dr. Lawrence Bonassar, Co-Founder of 3D Bio Therapeutics

Hod Lipson, Co-Founder of 3D Bio Therapeutics

Hod Lipson received his Ph.D. from the Technion-Israel Institute of Technology in 1999, followed by postdoctoral research at Brandeis University and MIT. He was a professor at Cornell University for 14 years and moved to Columbia University in 2015 as a professor of mechanical engineering and data science.

Image source: Alan Turing Institute, Hod Lipson, Co-Founder of 3D Bio Therapeutics
Image source: Alan Turing Institute, Hod Lipson, Co-Founder of 3D Bio Therapeutics

The Entrepreneurial Story of 3D Bio Therapeutics — Nothing happens overnight

The project started as early as 2000. Daniel Cohen was an undergraduate student working on 3D printing of non-traditional materials in the lab of Hod Lipson, a robotics expert who builds autonomous robots. Lawrence Bonassar is a bioengineer who had implanted cartilage shaped like a human ear into the backs of rats in 1997. He came to Cornell University in 2003. The three hit it off, and after more than a decade of research, an early version of the 3D bioprinted ear was created using collagen derived from animal cartilage cells.

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